Scientists have found that about 250 diseases only occur in men. If you want to have a healthy boy, go to the hospital and check what kind of illness you have passed on to your son.
With the rapid development of genetics, more than 3,000 genetic diseases have been discovered, of which about 250 are exclusively in men, and women have little or no disease. Why is this
Genetic diseases that are only inherited for men
There are 23 pairs of chromosomes in human cells, of which 1 pair (2) are gender-specific sex chromosomes, females are XX, and males are XY. More than 50,000 genes that determine various human traits are carried on chromosomes. If the gene is mutated, the disease can develop and it can be passed on to future generations. If the causative gene is on the sex chromosome, there will be a genetic association. The causative gene is on the X chromosome, which is called X-linked or X-linked genetic disease. As long as one X chromosome carries a pathogenic gene, it can be called an X-linked dominant genetic disease. This disease is rare, and both men and women can develop the disease. Only the two X chromosomes are called X-linked recessive genetic diseases that are caused by pathogenic genes. This disease is more common. Since it is difficult for a woman to encounter a pathogenic condition in the same position on both chromosomes, an X-chromosome-causing gene is often masked by another normal gene on the X-chromosome, so no symptoms are shown, but the causative genes are carried. And deliverers. Unlike males, there is only one X chromosome. If there is a pathogenic gene on it, there is no corresponding normal gene that can mask it. Usually if the mother is the carrier of the causative gene and the father is normal, one-half of the sons may be the patient, and one-half of the daughters may be carriers of the causative gene. This is why some diseases are only transmitted to men. There are many diseases that are only inherited to men. Here are some common diseases.
1, hemophilia
There is a lack of an important clotting factor in the patient’s blood—an anti-hemoglobin globulin. For example, if bleeding from trauma is caused by various reasons, the blood does not coagulate and eventually die due to excessive bleeding. At present, this protein can be supplied in large quantities, which greatly reduces the mortality rate.
2. Dummy large-scale progressive muscular dystrophy
It usually develops around the age of 4 and generally does not exceed 7 years old. The muscles of the thighs atrophied, the legs became thick and weak, and the walking posture was like a duck. Most patients die around the age of 20. Currently there is no effective treatment.
3, broad bean disease
It is an acute hemolytic anemia caused by eating broad beans. Due to the lack of glucose-6-phosphate dehydrogenase in the patient, the stability of the erythrocyte membrane is poor. Broad bean disease can occur at any age, but it is more common in children under 9 years of age. General food after 1 to 2 days after the onset of beans, light as long as no longer eat beans, 1 week to self-healing; severe severe anemia, yellow skin, hepatosplenomegaly, urine was soy sauce; more serious death . According to statistics, 90% of patients with faba bean disease are male, and some people use primaquine, aspirin, sulfa drugs, etc., and appear hemolytic anemia, which is the same genetic disease as faba bean disease.
4, red and green blind
Since the disease does not endanger life, the husband and wife are more likely to have pathogenic genes at the same time. In this way, the next generation of women will have the possibility of acquiring an X chromosome with a causative gene from their parents and thus be symptomatic. However, according to statistics, the incidence of males is 14 times that of women. This disease can affect young people's choice of profession and profession.
5. Congenital agammaglobulin disease, hereditary deafness, hereditary optic atrophy, etc., are also X-linked recessive genetic diseases.
In short, there is currently a lack of specific treatment for this type of disease. Therefore, we can only base ourselves on prevention and resolutely prevent close relatives from getting married. Women who have such a family history of genetic diseases or have children who have had a child who is sick have to do prenatal diagnosis when they re-pregnant. Generally, only female fetuses are retained to prevent children from being born with burdens on families and society. At present, foreign countries have been able to carry out intrauterine diagnostics, so that men who have not inherited genetic diseases can be preserved. Young people with a family history of inherited diseases should go to genetic counseling clinics before marriage. Patients with severe genetic diseases should not be married and have children. This is beneficial to the country. We believe that in the near future, with the rapid development of genetic engineering, gene therapy for genetic diseases, cutting off disease-causing genes and replacing them with normal genes can fundamentally solve the problem of treating genetic diseases.